| #1Zero Gravity Cannabis - MedicalSaco · York County | 43.0%231 of 516 squares | 6.0best 1 | 4.9 | 162 |
| #2Blossom Cannabis (Medical)Saco · York County | 36.6%195 of 516 squares | 7.0best 1 | 4.9 | 274 |
| #3Blossom Cannabis (Medical)Biddeford · York County | 25.5%138 of 516 squares | 7.5best 1 | 4.8 | 304 |
| #4Kind Acres Farm (Medical)Biddeford · York County | 17.7%102 of 516 squares | 7.4best 1 | 4.7 | 289 |
| #5Hidden GreensBuxton · York County | 14.7%79 of 516 squares | 9.2best 1 | 5.0 | 247 |
| #6Green Roots CompanyHollis · York County | 13.8%73 of 516 squares | 10.8best 1 | 4.9 | 86 |
| #7Beach Boys Cannabis Co.'s Beach Club - Old Orchard Beach (21+/Recreational Weed)Old Orchard Beach · York County | 12.3%69 of 516 squares | 9.3best 1 | 4.7 | 63 |
| #8The Maine Cannabis ShopCumberland County | 12.1%69 of 516 squares | 10.9best 1 | 5.0 | 44 |
| #9Coastal Roots Cannabis RetailYork County | 11.8%71 of 516 squares | 8.4best 1 | 4.4 | 293 |
| #10Stoner & Co. Recreational (21+) BiddefordBiddeford · York County | 11.2%61 of 516 squares | 7.8best 1 | 4.9 | 82 |
| #11First Class CannabisBiddeford · York County | 10.4%59 of 516 squares | 8.4best 1 | 4.5 | 13 |
| #12Ripple Wellness - Saco: Medical Cannabis DispensarySaco · York County | 10.1%55 of 516 squares | 10.3best 1 | 4.9 | 40 |
| #13The Farm Stand (Medical)Saco · York County | 9.2%54 of 516 squares | 9.0best 1 | 4.6 | 156 |
| #14Grass Monkey Cannabis CompanySouth Portland · Cumberland County | 7.5%46 of 516 squares | 11.8best 1 | 4.9 | 1,060 |
| #15Coastal RemediesScarborough · Cumberland County | 5.5%35 of 516 squares | 10.7best 1 | 4.6 | 208 |
| #16Ripple Wellness - Biddeford: Medical Cannabis StoreBiddeford · York County | 5.5%33 of 516 squares | 9.8best 1 | 4.6 | 37 |
| #17Undertow Cannabis Co. (Medical Cannabis)Biddeford · York County | 5.5%32 of 516 squares | 10.5best 1 | 4.9 | 138 |
| #18Maine Only Cannabis Shop Recreational 21+Hollis · York County | 4.7%24 of 516 squares | 13.6best 2 | 4.9 | 93 |
| #19Shannon's Best Buds (Medical Cannabis)Scarborough · Cumberland County | 4.5%26 of 516 squares | 9.8best 2 | 4.6 | 41 |
| #20The Shop at Pamolab (medical patients only)Scarborough · Cumberland County | 4.1%27 of 516 squares | 8.0best 1 | 5.0 | 10 |
| #21HIGHLY Recreational Dispensary (Adult use 21+) - South PortlandSouth Portland · Cumberland County | 3.6%28 of 516 squares | 9.3best 1 | 4.9 | 685 |
| #22First Class Cannabis (Medical)Saco · York County | 3.5%19 of 516 squares | 11.3best 1 | 4.6 | 40 |
| #23The DispensarySouth Portland · Cumberland County | 3.0%22 of 516 squares | 12.2best 2 | 4.7 | 37 |
| #24Norumbega Provisions (medical/appointment only)Scarborough · Cumberland County | 2.8%16 of 516 squares | 9.7best 3 | 5.0 | 8 |
| #25SeaWeed Co. - South Portland Recreational Cannabis DispensarySouth Portland · Cumberland County | 2.4%15 of 516 squares | 10.3best 1 | 4.6 | 360 |
| #26Landrace Cannabis - RecreationalBiddeford · York County | 2.3%15 of 516 squares | 11.6best 1 | 4.7 | 64 |
| #27Moby BotanicalsCumberland County | 2.2%15 of 516 squares | 8.2best 1 | 5.0 | 5 |
| #28Misty Patch(Med)Buxton · York County | 2.1%11 of 516 squares | 8.3best 2 | – | – |
| #29Kind Guy Patient Care CenterBiddeford · York County | 1.9%13 of 516 squares | 11.8best 1 | 4.8 | 185 |
| #30Pamolab Manufacturing (FOR OUR MEDICAL SHOP PLEASE SEARCH THE SHOP AT PAMOLAB)Cumberland County | 1.9%13 of 516 squares | 6.2best 2 | 4.9 | 20 |
| #31Beach Health CenterYork County | 1.9%10 of 516 squares | 10.8best 1 | 5.0 | 33 |
| #32Herbal Remedies of MaineGorham · Cumberland County | 1.6%9 of 516 squares | 10.9best 1 | 4.7 | 81 |
| #33Beach Fantasy BoutiqueYork County | 1.2%7 of 516 squares | 11.0best 1 | 5.0 | 1 |
| #34Casco Bay HempYork County | 0.8%5 of 516 squares | 13.5best 1 | 5.0 | 24 |
| #35Beach Boys Cannabis Co.: Recreational Weed + Medical Dispensary - South Portland/ ScarboroughSouth Portland · Cumberland County | 0.7%5 of 516 squares | 11.2best 1 | 4.6 | 175 |
| #36Rooted Heart Cafe & ApothecaryYork County | 0.3%2 of 516 squares | 7.4best 2 | 5.0 | 94 |
| #37Selective LLCSouth Portland · Cumberland County | 0.3%2 of 516 squares | 11.8best 1 | 5.0 | 216 |
| #38Grass Roots Marijuana - South Portland (21+)Cumberland County | 0.3%3 of 516 squares | 11.3best 2 | 4.9 | 594 |
| #39Theory Wellness - South Portland DispensarySouth Portland · Cumberland County | 0.3%3 of 516 squares | 11.3best 3 | 4.3 | 310 |
| #40Landrace Cannabis Co - RecreationalYork County | 0.2%2 of 516 squares | 10.5best 1 | 4.6 | 81 |
| #41Up North GardensCumberland County | 0.2%2 of 516 squares | 9.1best 3 | – | – |
| #42Tried & True - Medical CannabisScarborough · Cumberland County | 0.2%1 of 516 squares | 12.5best 1 | 4.9 | 52 |
| #43Potvin's MarketYork County | 0.2%1 of 516 squares | 7.1best 2 | 3.9 | 51 |
| #44Seaside Family Health CareYork County | 0.2%1 of 516 squares | 9.8best 3 | 4.0 | 32 |
| #45Leafwell - Medical Marijuana Card - ScarboroughCumberland County | 0.1%1 of 516 squares | 11.5best 2 | 4.9 | 227 |
| #46Bigsal’s Smoke ShopYork County | 0.1%2 of 516 squares | 5.8best 3 | 4.5 | 53 |
| #47Headies Medical Cannabis Dispensary (Biddeford)Biddeford · York County | 0.1%1 of 516 squares | 11.6best 3 | 4.8 | 50 |
| #48House of Hash (Medical)South Portland · Cumberland County | 0.1%1 of 516 squares | 10.8best 3 | 4.8 | 157 |
| #49ClearChoiceMD Urgent Care | ScarboroughCumberland County | 0.1%1 of 516 squares | 9.4best 3 | 4.8 | 1,516 |